Table 1.

Genotype distribution of H6PDH gene in PCOS and healthy controls.

Genotype	Controls (n=31)	Cases (n=74)	Odds ratio (C.I.)	P
acccaggc
+/+	23 (74.2%)	57 (77.6%)
+/−	8 (25.8%)	17 (22.4%)
−/−	0 (0%)	0 (0%)
Allele frequency difference			0.88 (0.36–2.15)	0.77
Risk of deletion			0.86 (0.33–2.26)	0.76
c.452a/c; p.D151A
a/a	27 (87.1%)	60 (81.6%)
a/c	4 (12.9%)	13 (17.1%)
c/c	0 (0%)	1 (1.3%)
Allele frequency difference			1.64 (0.52–5.14)	0.40
Risk of p.151A			1.58 (0.47–5.23)	0.46
c.1358g/a; p.R453Q
g/g	21 (67.7%)	45 (61.8%)
g/a	7 (22.6%)	24 (31.6%)
a/a	3 (9.7%)	5 (6.6%)
Allele frequency difference			1.12 (0.55–2.31)	0.75
Risk of p.453Q			1.35 (0.56–3.28)	0.50
c.1661c/t; p.P554L
c/c	27 (87.1%)	58 (78.9%)
c/t	4 (12.9%)	15 (19.7%)
t/t	0 (0%)	1 (1.3%)
Allele frequency difference			1.88 (0.61–5.84)	0.27
Risk of p.554L			1.86 (0.57–6.1)	0.30

C.I.: 95% conidence interval