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. 2010 Dec 8;20(4):806–819. doi: 10.1093/hmg/ddq524

Figure 4.

Figure 4.

Art-P70/p53 double-mutant mice are predisposed to thymic lymphomas with chromosomal translocations. (A) Decreased survival of Art-P70/p53 mice. Survival of a cohort of wild-type (n= 11), Art−/− (n= 10), p53−/− (n= 11), ArtP70/P70 (n= 14), ArtP70/P70p53−/− (n= 13) and Art−/−p53−/− (n= 9) mice was observed for a period of 40 weeks. Shown are Kaplan–Meier survival curves representing the percentage of survival of cohort mice versus age in weeks. (B) Distinct tumor spectrum exhibited by Art-P70/p53 mice. Table summarizing the number of the different tumor types observed in mice of the indicated genotypes.