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a Development of alopecia areata in 8-month-old C3H/HeJ mice upon heat treatment once daily for 12 consecutive days. Number of heat-treated mice = 35; number of sham-treated mice = 40. The percentages of mice with AA are shown for heat- and sham-treated mice (p < 0.0001). b–d Heat-induced alopecia areata in an 18-month-old C3H/HeJ mouse after six weekly heat treatment on the trunk (c) compared with a sham-treated mouse (b) and a mouse that developed AA spontaneously (d)
