Fig. 5.
Changes in UCP3 expression in myocardium and cardiomyocytes under stress. Compared with the control, the results from Western blotting showed a that the UCP3 level declined by 40% after 4 weeks of restraint stress in the rat myocardium (p < 0.05). b The UCP3 levels of mitochondria gradually declined with restraint-time prolongation in chronic stress groups to about 12%, 13%, and 48% inhibition of expression, respectively in the 2 weeks, 3 weeks and 4 weeks restraint groups (p < 0.05). c The UCP3 levels declined approximately to 82% in norepinephrine treated for 12 h (p < 0.05). d The UCP3 level significantly declined to 72% in cardiomyocytes treated with corticosterone (CORT) at 10−4 mol/L concentration for 12 h in vitro (p < 0.05). In all Western blots, uniformity of sample loading was confirmed by probing for tubulin or Cox-2