Fig. 1.

Oxidative stress markers at varying time intervals following neonatal UUO. TTA total antioxidant activity. Total Antioxidant activity was measured as percent inhibition of ABTS⁺, determined as: . See the “Materials and methods” and “Results” sections for further explanations. Lower antioxidant activity was shown in renal cortex from rats after 5 and 7 days of UUO (solid bars) related to controls (open bars), **p < 0.01 and intensive decrease on antioxidant activity was demonstrated after 10 and 14 days of obstruction vs. control, ***p < 0.001 both; 14-day obstructed kidney vs. contralateral kidney (shaded bars), ^†††p < 0.001. No differences were shown between control and contralateral cortex. The results shown are representative of four similar experiments