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. 2011 Jan;12(1):30–34. doi: 10.1038/embor.2010.199

Figure 2.

Figure 2

Pathogenetic framework, mechanisms and consequences of perinatal malprogramming, showing the etiological significance of perinatal overfeeding and hyperinsulinism for excess weight gain, obesity, diabetes mellitus and cardiovascular diseases in later life. Credit: Andreas Plagemann.