Table 3. Top results obtained for SNPs that showed a Rχ p-value<1E-4 and RM p-value<1E-2.
ROADTRIPS | MQLS | naive frequencies | BLUE frequencies | ||||||||||||||
ch | SNP | bp | genes | alleles | RM | Rχ | RW | Corr. χ2 | MQLS | cases | cont's | all sample | cases | cont's | unkn cont's | all sample | Hapmap (CEU) |
1 | rs12404212 | 244348886 | SMYD3 | A/G | 0.004620 | 0.000094 | 0.548685 | 0.000080 | 0.000061 | 0.22 | 0.16 | 0.11 | 0.15 | 0.11 | 0.07 | 0.07 | 0.08 |
2 | rs1915174 | 50451419 | NRXN1 | G/A | 0.002606 | 0.000028 | 0.000116 | 0.000023 | 0.000819 | 0.30 | 0.47 | 0.48 | 0.34 | 0.51 | 0.51 | 0.53 | 0.57 |
2 | rs12465806 | 50451831 | NRXN1 | A/G | 0.002432 | 0.000029 | 0.000119 | 0.000025 | 0.000755 | 0.30 | 0.47 | 0.48 | 0.34 | 0.51 | 0.52 | 0.53 | 0.56 |
2 | rs11125301 | 50452354 | NRXN1 | T/A | 0.001982 | 0.000025 | 0.000080 | 0.000020 | 0.000582 | 0.30 | 0.47 | 0.48 | 0.34 | 0.53 | 0.52 | 0.53 | 0.57 |
2 | rs1829534 | 50464580 | NRXN1 | C/T | 0.002602 | 0.000028 | 0.000122 | 0.000023 | 0.000818 | 0.30 | 0.47 | 0.48 | 0.34 | 0.51 | 0.51 | 0.53 | 0.58 |
2 | rs1402129 | 50470343 | NRXN1 | T/C | 0.003125 | 0.000042 | 0.000313 | 0.000035 | 0.001035 | 0.30 | 0.47 | 0.48 | 0.34 | 0.51 | 0.51 | 0.52 | 0.57 |
2 | rs1864466 | 203564702 | ALS2CR8 | A/G | 0.000657 | 0.000011 | 0.000125 | 0.000008 | 0.000001 | 0.32 | 0.14 | 0.17 | 0.26 | 0.10 | 0.09 | 0.09 | 0.08 |
2 | rs2359681 | 207274185 | DYTN, ADAM23 | T/C | 0.002540 | 0.000078 | 0.018889 | 0.000072 | 0.000140 | 0.30 | 0.18 | 0.17 | 0.22 | 0.18 | 0.13 | 0.13 | 0.15 |
6 | rs10946741 | 25118978 | LRRC16A-SLC17A4 | A/G | 0.000256 | 0.000091 | 0.064420 | 0.000087 | 0.000169 | 0.21 | 0.35 | 0.41 | 0.27 | 0.43 | 0.51 | 0.48 | 0.44 |
7 | rs16872208 | 7957012 | GLCCI1 | A/T | 0.009254 | 0.000071 | 0.000014 | 0.000061 | 0.002070 | 0.29 | 0.19 | 0.17 | 0.26 | 0.17 | 0.13 | 0.14 | 0.08 |
7 | rs17528240 | 10716439 | NDUFA4, PHF14 | G/A | 0.003906 | 0.000013 | 0.000010 | 0.000011 | 0.001173 | 0.57 | 0.38 | 0.39 | 0.50 | 0.37 | 0.36 | 0.36 | 0.28 |
7 | rs12673360 | 10802614 | NDUFA4, PHF14 | A/G | 0.006443 | 0.000015 | 0.000032 | 0.000012 | 0.002306 | 0.57 | 0.38 | 0.39 | 0.51 | 0.37 | 0.38 | 0.37 | 0.30 |
7 | rs6460751 | 10811628 | NDUFA4, PHF14 | G/A | 0.005312 | 0.000007 | 0.000007 | 0.000006 | 0.001823 | 0.58 | 0.37 | 0.39 | 0.53 | 0.37 | 0.38 | 0.38 | 0.30 |
8 | rs1484190 | 2879144 | CSMD1 | T/A | 0.002964 | 0.000042 | 0.024529 | 0.000040 | 0.001511 | 0.60 | 0.39 | 0.40 | 0.62 | 0.35 | 0.35 | 0.36 | 0.42 |
8 | rs12707927a | 129274206 | PVT1 | A/G | 0.006739 | 8.95E-08 | 0.031231 | 6.49E-08 | 0.004214 | 0.16 | 0.05 | 0.05 | 0.08 | 0.04 | 0.07 | 0.06 | 0.06 |
10 | rs11239832 | 42739373 | BMS1 | T/G | 0.006675 | 0.000069 | 0.064082 | 0.000057 | 0.000746 | 0.23 | 0.09 | 0.12 | 0.22 | 0.09 | 0.08 | 0.10 | 0.12 |
10 | rs12784847 | 72181534 | ADAMTS14 | A/G | 0.004672 | 0.000072 | 0.331840 | 0.000069 | 0.002452 | 0.50 | 0.35 | 0.31 | 0.40 | 0.32 | 0.30 | 0.28 | 0.30 |
10 | rs3740434 | 72192195 | ADAMTS14 | T/C | 0.000808 | 0.000076 | 0.193978 | 0.000073 | 0.000226 | 0.55 | 0.37 | 0.36 | 0.46 | 0.35 | 0.31 | 0.29 | 0.41 |
10 | rs11591930 | 72198570 | ADAMTS14 | A/T | 0.000224 | 0.000026 | 0.152853 | 0.000025 | 0.000037 | 0.55 | 0.37 | 0.35 | 0.46 | 0.35 | 0.29 | 0.27 | 0.26 |
12 | rs1358652 | 126947387 | - | C/T | 0.001398 | 0.000014 | 0.148832 | 0.000011 | 0.000139 | 0.18 | 0.07 | 0.08 | 0.16 | 0.04 | 0.06 | 0.06 | 0.14 |
12 | rs764377 | 126947603 | - | A/G | 0.001194 | 0.000013 | 0.134585 | 0.000010 | 0.000092 | 0.18 | 0.07 | 0.08 | 0.16 | 0.04 | 0.06 | 0.07 | 0.14 |
12 | rs1463670a | 126948493 | - | C/A | 0.000692 | 0.000025 | 0.210417 | 0.000024 | 0.000288 | 0.20 | 0.07 | 0.08 | 0.18 | 0.04 | 0.08 | 0.08 | 0.14 |
12 | rs1463669a | 126948655 | - | G/A | 0.000707 | 0.000026 | 0.211419 | 0.000025 | 0.000289 | 0.20 | 0.07 | 0.08 | 0.18 | 0.04 | 0.08 | 0.08 | 0.14 |
12 | rs1463666 | 126949325 | - | C/T | 0.001194 | 0.000013 | 0.134585 | 0.000010 | 0.000092 | 0.18 | 0.07 | 0.08 | 0.16 | 0.04 | 0.06 | 0.07 | 0.14 |
13 | rs2503340 | 21708964 | - | G/T | 0.002605 | 0.000023 | 0.000112 | 0.000019 | 0.000531 | 0.49 | 0.36 | 0.33 | 0.44 | 0.31 | 0.29 | 0.29 | 0.17 |
14 | rs7146962 | 53215067 | - | G/A | 0.003006 | 0.000090 | 0.000017 | 0.000077 | 0.000907 | 0.64 | 0.44 | 0.47 | 0.63 | 0.40 | 0.43 | 0.43 | 0.24 |
22 | rs12167903a | 29096466 | CCDC157 | T/C | 0.000450 | 0.000056 | 0.000021 | 0.000054 | 0.000001 | 0.15 | 0.07 | 0.05 | 0.13 | 0.05 | 0.02 | 0.02 | 0.00 |
Naïve and BLUE allele frequencies and are shown.
aROADTRIPS gives a warning for Rχ.