Table 5.
Phospholipid and ceramide levels in the feces of mice fed the high-fat diet alone (HF) or the high-fat diet supplemented with milk phospholipids (HFPL) in the form of phospholipid-rich dairy milk extract (PLRDME)
HF | HFPL | difference | |
---|---|---|---|
nmol/mouse/day | |||
Phosphatidylcholine | 71 ± 7 | 272 ± 22 *** | +281% |
Lysophosphatidylcholine | 60 ± 7 | 92 ± 8 ** | +52% |
Phosphatidylethanolamine | 7 ± 1 | 13 ± 1 ** | +79% |
Phosphatidylinositol | 3.1 ± 0.4 | 22.5 ± 2.6 *** | +617% |
Phosphatidylserine | 3.3 ± 0.3 | 4.8 ± 0.4 * | +43% |
Sphingomyelin | 55 ± 5 | 362 ± 34 *** | +560% |
Ceramide | 29 ± 2 | 150 ± 13 *** | +424% |
Monohexosylceramide | 10 ± 1 | 100 ± 8 *** | +934% |
Dihexosylceramide | 23 ± 1 | 258 ± 15 *** | +1017% |
Trihexosylceramide | 0.8 ± 0.1 | 2.5 ± 0.2 *** | +212% |
Results represent means ± SEM for 11 fecal samples in each group. Percentage difference between groups is given in italics. Significant difference between HF and HFPL by Student's t-test: * P < 0.05, ** P < 0.01, *** P < 0.001.