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. Author manuscript; available in PMC: 2012 Jan 1.
Published in final edited form as: Nat Methods. 2010 Dec 20;8(1):35–38. doi: 10.1038/nmeth.f.326

figure 1.

figure 1

Modes of light-regulated biochemistry. (a) Protein activity can be put directly under light control by fusion to light-responsive domains or residues (green). Upon stimulation with light (gold arrow), allosteric inhibition is removed, leading to activation. (b,c) Protein activity can be indirectly controlled using light-dependent anchoring to a subcellular compartment (b) or scaffolding (c).