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. 2011 Jan 20;34(2):418–423. doi: 10.2337/dc10-1013

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© 2011 by the American Diabetes Association.

Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. See http://creativecommons.org/licenses/by-nc-nd/3.0/ for details.

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Incidence of type 2 diabetes during the intervention period of 4 years (A) (end indicated by a vertical line) and during the entire follow-up period (B) by FH and randomization group (intervention vs. control) in the DPS. Solid line is for the control group. During the intervention follow-up of 4 years on average, intervention had significant effect on the incidence of type 2 diabetes in the FH+ group (P = 0.0002, *P = 0.0008) but not in the FH- group (P = 0.61, *P = 0.11). During the entire follow-up, intervention had an effect in both FH+ (P = 0.0004, *P = 0.002) and FH− (P = 0.13, *P = 0.006) groups. P is from Kaplan–Meier analysis, *P after adjustment for age, sex, baseline BMI, baseline fasting glucose, and study center in Cox regression model.