Table 1. Cell-cycle related proteins predicted as targets for miR-17, miR-20a, and miR-106b and chosen for experimental target gene validation.
| hsa-miR-17: | hsa-miR-20a: | hsa-miR-106b: |
| proproliferative: | ||
| CCND1* | CCND1 | CCND1 |
| CCND2 | CCND2 | CCND2 |
| E2F1* | E2F1* | E2F1* |
| E2F3 | E2F3* | E2F3 |
| antiproliferative: | ||
| CDKN1A* | CDKN1A* | CDKN1A* |
| MAPK9* | MAPK9 | MAPK9 |
| PTEN* | PTEN | PTEN |
| RB1 | RB1 | RB1 |
| RBL1 | RBL1 | RBL1 |
| RBL2* | RBL2 | RBL2 |
| WEE1 | WEE1 | WEE1 |
Predictions already validated in scientific literature are denoted by an asterisk (*, see main text for details).