Table 3. Hazard ratio and 95% confidence interval (CI) for composite cardiovascular end-point and mortality according to each risk allele in the entire population and in diabetic and non-diabetic individuals.* .
Non-diabetic subjects | Diabetic subjects | Entire population | |||||||
HR | 95%CI | P value | HR | 95%CI | P value | HR | 95%CI | P value | |
Composite Cardiovascular events | |||||||||
Number of alleles | 1.163 | 1.02–1.32 | 0.022 | 1.034 | 0.87–1.22 | 0.696 | 1.113 | 1.01–1.28 | 0.033 |
Number of alleles - no TCF7L2 | 1.125 | 0.99–1–29 | 0.084 | 1.049 | 0.88–1.26 | 0.594 | 1.104 | 0.99–1.22 | 0.061 |
(*) adjusted by age, gender, arterial hypertension, BMI, total cholesterol, HDL, LDL, triglycerides, previous MI, smoking and fasting glycemia.