Table 5.
Chronic Neurotoxicity/Neurologic Deterioration and Brain Mets at 12 Month
| Treatment Arm | Brain Mets Status | No Neurologic Deterioration |
Neurologic Deterioration |
No Chronic Neurotoxicity |
Chronic Neurotoxicity |
||||
|---|---|---|---|---|---|---|---|---|---|
| n | % | n | % | n | % | n | % | ||
| 2.5 Gy × 10 | No brain mets | 76 | 74 | 26 | 93 | 76 | 73 | 26 | 96 |
| Brain mets | 27 | 26 | 2 | 7 | 28 | 27 | 1* | 4 | |
| 2.0 Gy × 18 | No brain mets | 44 | 88 | 16 | 94 | 44 | 88 | 16 | 94 |
| Brain mets | 6 | 12 | 1 | 6 | 6 | 12 | 1* | 6 | |
| 1.5 Gy × 24 | No brain mets | 37 | 76 | 15 | 88 | 37 | 76 | 15 | 88 |
| Brain mets | 12 | 24 | 2 | 12 | 12 | 24 | 2 | 12 | |
*
Brain metastasis developed after Month 12 evaluation
Mets = metastasis