Table 3. Obesity susceptibility loci identified in GWAS tested by logistic regression for association with PCOS in the case-control cohort (395 cases, 176 controls).

			ADDITIVE				DOMINANT				RECESSIVE
Gene	SNP	Minor allele	N	OR	STAT	P	N	OR	STAT	P	N	OR	STAT	P
FTO	rs1421085	C	571	0.830	−1.080	0.280	571	0.633	−1.819	0.069	571	1.134	0.385	0.700
	rs17817449	G	571	0.834	−1.040	0.298	571	0.646	−1.725	0.084	571	1.116	0.337	0.736
	rs8050136	A	571	0.842	−0.985	0.325	571	0.657	−1.670	0.095	571	1.134	0.382	0.702
	rs9939609	A	571	0.820	−1.137	0.256	571	0.635	−1.799	0.072	571	1.088	0.258	0.796
	rs9930506	G	571	0.844	−0.972	0.331	571	0.642	−1.686	0.092	571	1.103	0.318	0.751
GNPDA2	rs10938397	G	571	1.141	0.775	0.439	571	1.020	0.082	0.935	571	1.536	1.316	0.188
KCTD15	rs11084753	A	570	1.345	1.662	0.096	570	1.607	2.053	0.040	570	1.088	0.220	0.826
MC4R	rs17782313	C	571	1.341	1.459	0.145	571	1.450	1.564	0.118	571	1.259	0.410	0.682
	rs12970134	A	571	1.377	1.645	0.100	571	1.619	2.041	0.041	571	0.979	−0.044	0.965
MTCH2	rs10838738	G	571	1.062	0.359	0.720	571	1.044	0.189	0.851	571	1.171	0.454	0.650
NEGR1	rs2815752	G	571	0.953	−0.294	0.769	571	0.962	−0.167	0.867	571	0.898	−0.342	0.732
SH2B1	rs7498665	G	571	0.947	−0.326	0.744	571	1.011	0.046	0.963	571	0.788	−0.717	0.474
TMEM18	rs6548238	T	571	0.817	−0.949	0.343	571	0.728	−1.304	0.192	571	1.599	0.634	0.526