Table 4. Obesity susceptibility loci identified in GWAS tested by linear regression for association with BMI in 395 women with PCOS.

			ADDITIVE				DOMINANT				RECESSIVE
Gene	SNP	Minor allele	N	BETA	STAT	P	N	BETA	STAT	P	N	BETA	STAT	P
FTO	rs1421085	C	395	0.049	2.521	0.012	395	0.040	1.391	0.165	395	0.101	2.876	0.004
	rs17817449	G	395	0.043	2.188	0.029	395	0.033	1.148	0.252	395	0.092	2.569	0.011
	rs8050136	A	395	0.046	2.362	0.019	395	0.038	1.312	0.190	395	0.095	2.684	0.008
	rs9939609	A	395	0.047	2.412	0.016	395	0.040	1.385	0.167	395	0.095	2.684	0.008
	rs9930506	G	395	0.024	1.227	0.221	395	0.014	0.485	0.628	395	0.056	1.606	0.109
GNPDA2	rs10938397	G	395	0.034	1.726	0.085	395	0.056	1.894	0.059	395	0.028	0.843	0.400
KCTD15	rs11084753	A	394	−0.014	−0.666	0.506	394	−0.030	−1.112	0.267	394	0.013	0.319	0.750
MC4R	rs17782313	C	395	0.026	1.155	0.249	395	0.024	0.887	0.376	395	0.064	1.108	0.268
	rs12970134	A	395	0.041	1.940	0.053	395	0.031	1.152	0.250	395	0.118	2.428	0.016
MTCH2	rs10838738	G	395	0.005	0.239	0.811	395	0.021	0.762	0.447	395	−0.025	−0.625	0.532
NEGR1	rs2815752	G	395	−0.024	−1.187	0.236	395	−0.006	−0.225	0.823	395	−0.082	−2.069	0.039
SH2B1	rs7498665	G	395	0.007	0.343	0.732	395	0.016	0.568	0.570	395	−0.005	−0.124	0.901
TMEM18	rs6548238	T	395	0.019	0.773	0.440	395	0.009	0.309	0.758	395	0.117	1.542	0.124