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Correlation between MGMT promoter hypermethylation status and TP53 mutation status
| MGMT hypermethylated (n = 29)a | MGMT not hypermethylated (n = 20) | P value | |
|---|---|---|---|
| TP53 mutated | 21 | 16 | 0.77 |
| G:C>A:T mutation | 10 | 9 | 0.80 |
| G>A transition | 7 | 2 | |
| At CpG site | 7 | 2 | |
| C>T transition | 3 | 7 | |
| At CpG site | 3 | 5 | |
| TP53 not mutated | 7 | 4 |
aCase 10: no data on TP53 mutation could be obtained
