Table 4.

Univariate analyses of the effect of potential confounding variables on rates of neurologic, endocrinologic, vascular, and visual morbidity in the published literature

	Neurologic	Endocrine	Vascular	Visual
# Patients in study
1–10	9%	2%	1%	6%
11–20	2%	7%	0%	2%
21+	1%	1%	0%	4%
	P < 0.001	P < 0.01	P = 0.12	P = 0.45
Patient age
0–2	9%	48%	0%	4%
2.1–5	5%	41%	0%	0%
5.1–10	5%	44%	1%	2%
11–20	5%	34%	0%	2%
21–50	5%	37%	1%	4%
51+	2%	31%	0%	3%
	P = 0.84	P = 0.41	P = 0.85	P = 0.73
Tumor size
<3 cm	0%	36%	0%	6%
≥3 cm	10%	43%	2%	0%
	P = 0.06	P = 0.33	P = 0.59	P = 0.16
Hypothalamic involvement
Minor or none	5%	40%	5%	3%
Extensive	5%	33%	5%	5%
	P = 0.50	P = 0.09	P = 0.43	P = 0.35