Table 5.
Multivariate logistic regression demonstrating the risk of neurologic and endocrinologic morbidity controlling for extent of resection, study size, and presence of extensive hypothalamic involvement
| OR | 95% CI | P-value | ||
|---|---|---|---|---|
| − | + | |||
| Neurologic | ||||
| GTR | 5.05 | 1.15 | 22.21 | 0.03 |
| STR | 2.41 | 0.45 | 12.79 | 0.30 |
| Study size 1–10 | 2.54 | 1.02 | 6.29 | 0.04 |
| Study size 11–20 | 0.31 | 0.06 | 1.53 | 0.15 |
| Endocrine | ||||
| Extensive hypothalamic involvement | 1.28 | 0.78 | 2.08 | 0.33 |
| GTR | 3.45 | 2.05 | 5.81 | <0.00001 |
| STR | 1.89 | 1.05 | 3.38 | 0.03 |
| Study size 1–10 | 1.02 | 0.66 | 1.58 | 0.92 |
| Study size 11–20 | 0.61 | 0.35 | 1.05 | 0.08 |
Note that the odds ratio for the GTR and STR groups are expressed relative to the STR + XRT group, and that the odds ratios for the study size groups are expressed relative to studies with the group with the largest study size