Fig. 3.

Ovarian and colon cancer biopsies were stained with polyclonal antibody against CDR2. There was no binding of the secondary antibody alone to ovarian cancer (a). The same ovarian cancer from a patient with Yo antibodies, but no PCD showed CDR2 staining of cytoplasm and nuclei of the cancer cells (b). This biopsy also contained normal ovarian tissue with slight CDR2 staining of stromal cells and strong CDR2 staining of epithelial cell (c). Two other ovarian cancers from patients with PCD and Yo antibodies showed nuclear CDR2 staining of the cancer cells (d, e). Colon cancer cells also expressed nuclear and cytoplasmic CDR2 staining (f)