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. Author manuscript; available in PMC: 2011 Jan 21.
Published in final edited form as: Bioconjug Chem. 2007 Nov 21;18(6):2159–2168. doi: 10.1021/bc700233w

Table 3.

Labeling Efficiencies of an Oligonucleotide with ZnPc 2 at Different Buffer and pH Conditionsa

pH borate carbonate
7.5 67 ± 2%
8.0 26 ± 3%
8.5 38 ± 6% 59 ± 2%
9.5 15 ± 1% 36 ± 2%
a

The conjugation reactions used a C6H12 linker, ZnPc 2, succinimidyl ester 4, and an MPc/oligonucleotide molar ratio of 9:1.