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. 2011 Jan 3;108(3):1176–1181. doi: 10.1073/pnas.1013965108

Fig. 1.

Fig. 1.

A band of Mac-2–expressing astrocytes is located at the postlaminar optic nerve MTZ. (A) Mac-2–expressing cells form a band at the MTZ, as determined by the expression of the astrocyte-specific Vim mRNA and the oligodendrocyte-specific Plp mRNA. Histogram shows the expression of Vim mRNA (solid red), Plp mRNA (dotted red), and Mac-2 (green) as a function of distance from the center of Mac-2 expression. Values represent the mean of mean values from 10 nerves (an average of six sections per nerve). (B) Mac-2–expressing cells at the MTZ are astrocytes, based on the expression of astrocyte-specific Vim and Aldh1l1 mRNAs and lack of expression of the microglial marker Iba1. All images of the ONH in all figures are oriented with the eye to the left of the MTZ. (Scale bars: A, 100 μm; B, 10 μm.)