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. Author manuscript; available in PMC: 2011 Jan 21.
Published in final edited form as: J Trauma. 2010 Jan;68(1):35–41. doi: 10.1097/TA.0b013e3181bbbddb

Figure 1.

Figure 1

(A) Effect of estrogenic hormonal manipulation on KEI showing that ovariectomy impairs RBC deformability after T/HS and that the effect of ovariectomy is abrogated by estrogen and the ER-β agonist to a greater degree than the ER-α agonist. N = 7–8 rats per group with data expressed as mean ± SD. *p < 0.05 vs. all other groups and #p < 0.05 vs. T/SS group. (B) Effect of estrogenic hormonal manipulation on T/HS-induced RBC elongation (EI) at 0.03 Pa showing that ovariectomy reduced the ability of RBC to elongate normally and that this defect in deformability was fully reversed by estradiol but only partially reversed by the ER-α or -β agonists. N = 7–8 rats per group with data expressed as mean ± SD. *p < 0.05 vs. all other groups and **p < 0.05 vs. T/SS group, #p < 0.05 vs. T/SS and T/HS groups.