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The replication fork-associated factors TOF1, RRM3, CSM3, and DIA2 contribute to the maintenance of telomere length homeostasis. Autoradiogram of a Southern blot showing the relative length of telomeres in the WT, dia2Δ, dia2Δtof1Δ, dia2Δcsm3Δ, tof1Δ, csm3Δ, rrm3Δ, rrm3Δtof1Δ, and rrm3Δcsm3Δ strains; telomere lengths were analyzed by restriction digestion of genomic DNA by XhoI or PstI restriction enzymes and developed by hybridization to a labeled telomere-specific probe.
