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Schematics showing the mathematical hierarchy of cellular dynamics based on the chemical master equation (CME) approach. (a) Stochastic dynamics based on the Gillespie algorithm; (b) deterministic dynamics tending to attractors; (c) probabilistic distributions for the two attractors; (d) stochastic dynamics among the attractors. (a–c) represent stochastic molecular signalling, deterministic biochemical dynamics, and stochastic cellular evolution, respectively.
