Table 3.
Glycan epitope pattern of Cy5 labeled ACT
| Glycan epitope | CTR 1 | AD 1 | CTR 2 | AD 2 |
|---|---|---|---|---|
| N-linked: | ||||
| Bi Antennary | Not Detected | Not Detected | Not Detected | Not Detected |
| Tri/Tetra Antennary | High | High | High | High |
| High Mannose | Not Detected | Not Detected | Not Detected | Not Detected |
| Sialic Acid | High | Medium | High | Medium |
| Terminal GlcNAc | Low | Low | Low | Not Detected |
| Terminal GalNAc | Not Detected | Not Detected | Not Detected | Not Detected |
| Bisecting GlcNAc | Not Detected | Not Detected | Not Detected | Not Detected |
| O-Glycans | Not Detected | Not Detected | Not Detected | Not Detected |
Glycan profile produced for ACT using the Qproteome Glycoarray method.
ND=not detected (up to 10%); Low=11-30%; Medium=31-70%; High=71-100%