Figure 2. Stimulation of α4β1 and α5β1 integrins leads to FAK-dependent changes in macrophage morphology.

(A) Representative fields of CSF-1-starved WT and FAK^−/− BMMs following 5 min stimulation with the indicated GST proteins. Cells were fixed and stained for phalloidin. Cell elongation (B) and polarization (C) were determined as described in Materials and Methods. *Values significantly different from WT cells treated with GST; ^values significantly different from WT cells under the same treatment conditions; n = 3–4.