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. 2011 Jan 21;6(1):e16306. doi: 10.1371/journal.pone.0016306

Figure 2. Comparative regulation of secreted MMP-3 and -9 in Hp-infected AGS cells by curcumin and TT.

Figure 2

AGS cells cocultured with SS1 Hp strain were pretreated with curcumin or TT or only-antibiotics or omeprazole and the MMP levels in the conditioned media after 24 h were assessed. Concentrated conditioned media were analyzed by casein (A) and gelatin (B) zymography. Histographic representation of caseinolytic (C) and gelatinolytic (D) activities from the above zymogram and two other representative zymograms from independent experiments. Error bars = ±SEM. *, p<0.001; ns, nonsignificant vs. AGS cells alone. **, p = 0.0002 and ***, p = 0.0003 vs curcumin treated Hp infected AGS cells.