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. 2011 Jan 21;6(1):e16306. doi: 10.1371/journal.pone.0016306

Figure 7. Regulation of MMP-3 and -9 via NF-kB dependent mechanism by curcumin-therapy in Hp-infected mice.

Figure 7

Two weeks SS1-infected mice groups were treated with curcumin or TT or only-antibiotics for 7-days and the expressions of IL-1β, TNF-α, IL-8, and iNOS proteins were assessed by Western blot (A). Histographic representation of protein fold changes from the above blots and two other representative blots from independent experiments (B). Error bars = ±SEM. *, p<0.001; $, p<0.01; ns, nonsignificant vs. appropriate control. NFκB activation in the nuclear extracts of respective tissues using EMSA (C). Western blot analysis of NFκB(p65), IκBα and PPARγ proteins in Tx extracts and c-Fos and c-Jun proteins in the nuclear extracts of respective tissues while actin served as loading-control (D).