. Author manuscript; available in PMC: 2012 Mar 1.

Published in final edited form as: J Affect Disord. 2011 Mar;129(1-3):205–212. doi: 10.1016/j.jad.2010.09.010

Table 5.

Rates of clinical depression over time in relation to liver disease progression^*

Study Visit	No Liver Disease progression		Yes Liver Disease progression
	N	Number depressed (%)	N	Number depressed (%)
Baseline	85	21 (24.7)	36	10 (27.8)
12 month	83	20 (24.1)	36	14 (38.9)
24 month	80	19 (23.8)	33	11 (33.3)
36 month	77	22 (28.6)	30	12 (40.0)
48 month	70	17 (24.3)	26	10 (38.5)

After controlling for baseline clinical depression rates (p<0.001), the percentage of people with clinical depression was significantly higher among patients with liver disease progression (p=0.016) compared to those without progression in their liver disease using ANOVA modeling. The proportions did not change over time (p=0.82), nor was there an interaction between time and liver disease progression (p=0.98).