Table 5. The Reduction of Fluorescein Leakage by 2 or More Steps in Eyes With at Least Stage 2 Severity of Macular Edema at Baseline in Those Subjects Assigned to Celecoxib Treatment^*.

Month	Covariate Adjustment Factors	OR†	95% CI for OR	P
12	None	2.45	0.99−6.09	0.054
	Baseline severity and year	2.43	0.98−6.07	0.056
	Baseline severity, year, and laser treated	2.47	0.99−6.15	0.052
24	None	3.31	1.54−7.12	0.002
	Baseline severity and year	3.50	1.59−7.67	0.002
	Baseline severity, year, and laser treated	3.52	1.61−7.71	0.002
36	None	3.60	1.71−7.59	0.001
	Baseline severity and year	3.74	1.73−8.10	0.001
	Baseline severity, year, and laser treated	3.75	1.73−8.11	0.001

^*Analysis of variance model for repeated measures.

^†Reference group is placebo.

CI, confidence interval.