Table 6.

Cytotoxicity of fluorinated quassinoids

Compound	R1	R2	log GI50a
28	H		−7.7 ∼ −8.6
30	H		−7.0 ∼ −8.7
30	H		−5.0 ∼ −8.6
31		H	−4.8 ∼ −5.9
32		H	−4.5 ∼ −6.4

^aData from the NCI human tumor cell panel, including leukemia, nonsmall-cell lung cancer, colon cancer, CNS cancer, and others