Table 1.
Treatments | Dose mg/kg | Blood glucose concentration (mg/dl) | ||||
---|---|---|---|---|---|---|
0 h | 0.5 h | 1 h | 2 h | 3 h | ||
Gluc. control | -- | 89.80 ± 3.02 | 144.40 ± 4.85 | 150.60 ± 4.01 | 124.40 ± 3.32 | 105.20 ± 4.77 |
Glibenclamide | 5 | 90.20 ± 3.59 | 105.20 ± 3.49** | 92.20 ± 4.60** | 78.40 ± 4.20** | 66.20 ± 3.68** |
MC-P | 400 | 90.80 ± 4.18 | 128.80 ± 5.74 | 125.40 ± 4.38* | 108.20 ± 6.32 | 98.40 ± 3.22 |
MC-C | 400 | 88.80 ± 4.28 | 144.40 ± 5.80 | 131.80 ± 4.22 | 122.20 ± 6.77 | 95.20 ± 4.84 |
MC-A | 400 | 84.40 ± 4.41 | 141.20 ± 5.88 | 138.20 ± 5.20 | 120.80 ± 5.86 | 96.80 ± 4.83 |
MC-E | 400 | 88.20 ± 3.18 | 111.80 ± 5.20* | 109.20 ± 3.20** | 85.40 ± 3.12** | 85.60 ± 3.88* |
MC-Aq | 400 | 90.80 ± 4.88 | 166.20 ± 6.20 | 144.20 ± 5.20 | 124.60 ± 4.28 | 100.20 ± 3.84 |
MC -CAq | 400 | 88.60 ± 4.24 | 134.20 ± 4.86 | 121.40 ± 5.22* | 110.40 ± 4.88 | 90.20 ± 5.20 |
Each value represents the mean ± S.E.M. of five observations.
P<0.05,
P<0.01 vs control. MC - Michelia champaca, P - Petroleum ether (60-80o), C - Chloroform, A - Acetone, E - Ethanol, Aq - Aqueous, CAq - Crude aqueous