Table 3.
Parameters | Experimental groups | ||||
---|---|---|---|---|---|
Normal control | Diabetic control | M. champaca-ethanol | Glibenclamide | ||
5mg/kg | 200 mg/kg | 400 mg/kg | |||
Blood glucose | 81.40 ± 3.22** | 512.00 ± 15.29 | 320.00 ± 14.40** | 298.20 ± 12.20** | 124.40 ± 7.84** |
S. urea | 30.20 ± 1.77** | 279.00 ± 14.01 | 165.30 ± 6.26** | 143.20 ± 5.40** | 32.80 ± 1.39** |
S. creatinine | 0.45 ± 0.03** | 1.85 ± 0.36 | 0.88 ± 0.04* | 0.81 ± 0.03* | 0.44 ± 0.03** |
S. cholesterol | 34.00 ± 1.74** | 84.00 ± 4.94 | 99.20 ± 5.23 | 72.60 ± 3.43** | 32.20 ± 2.49** |
S. triglyceride | 33.40 ± 3.45** | 123.00 ± 6.63 | 93.20 ± 4.61* | 94.60 ± 4.81* | 38.20 ± 1.90** |
HDL | 24.60 ± 1.47** | 10.20 ± 1.12 | 14.00 ± 0.65** | 15.20 ± 2.44** | 25.80 ± 0.98** |
LDL | 22.00 ± 2.10** | 58.80 ± 3.22 | 42.20 ± 1.24** | 34.20 ± 1.61** | 23.60 ± 1.90** |
Hemoglobin | 11.20 ± 0.33** | 6.90 ± 0.41 | 7.30 ± 0.45 | 8.80 ± 0.68* | 10.90 ± 0.47** |
Gly. hemoglobin | 1.92 ± 0.17** | 5.70 ± 0.37 | 4.20 ± 0.38* | 3.20 ± 0.44** | 2.00 ± 0.15** |
Each value represents the mean ± S.E.M. of five observations.
P<0.05,
P<0.01 vs diabetic control (ANOVA followed by Dunnett's test)