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. 2010 Oct 26;22(1):84–92. doi: 10.1089/hum.2010.097

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Copyright 2011, Mary Ann Liebert, Inc.

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FIG. 3. — Effects of hPTH gene transfer on serum calcium in parathyroidectomized (PTX) rats. Blood was collected before and 2 days after Ad.hPTH-mediated gene transfer to both parotid glands of PTX animals (10¹¹ VP per gland) and serum was assayed for calcium. In (A), values for individual rats (n = 7) are shown before vector treatment and joined by a line to values in the same animal after vector treatment. All individual rats had higher serum calcium levels after vector treatment. This resulted in a significant (*p < 0.01) average increase of 32% in serum calcium levels in treated animals compared with saline-treated rats (n = 8), reaching levels similar to those of intact control animals (n = 5; B).