Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
TM values of RNA duplexes doubly and triply modified at positions 4, 11 and/or 16 of the caspase-2 guide sequence compared to native U:A base pairs in these positions. The passenger strand has either Y = C (green bars) or A (blue bars) opposite the modified site X, in which the R group on N2 of OG is H (X = O), propyl (X = P), or benzyl (X = B).
