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. Author manuscript; available in PMC: 2011 Nov 10.
Published in final edited form as: Annu Rev Cell Dev Biol. 2010 Nov 10;26:689–719. doi: 10.1146/annurev-cellbio-100109-104113

Figure 2.

Figure 2

The primate color vision and mouse olfactory systems utilize stochastic locus selection and locus control region (LCR)-mediated mechanisms. (a) Stochastic photopigment selection in New World primates requires locus selection and X inactivation. (b) Stochastic photopigment selection in Old World primates requires locus selection and LCR-mediated exclusive activation. (c) Stochastic expression of blue, red, and green photopigments in humans (adapted from Roorda & Williams 1999). (d) Stochastic olfactory receptor selection in mice requires locus selection and H region/LCR-mediated activation. (e) Functional olfactory receptors feed back to repress expression of other olfactory receptor gene alleles. (f) Stochastic expression of olfactory receptors in mice (courtesy of T. Ishii and P. Mombaerts, The Rockefeller University). Enh, enhancer.