Skip to main content
. Author manuscript; available in PMC: 2011 Apr 1.
Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2010 Sep 2;19(10):2549–2561. doi: 10.1158/1055-9965.EPI-10-0407

FIGURE 1. One-carbon metabolism and related enzymes and genetic polymorphisms.

FIGURE 1

Cysta, cystathionine; CBS, cystathionine ß-synthase; CH2THF, methylenetetrahydrofolate; CH3THF, methyltetrahydrofolate; MTHFR, methylenetetrahydrofolate reductase (provision of 5-methylfolate for homocysteine remethylation); MTR, methionine synthase (remethylation of homocysteine to methionine); MTRR, methionine synthase reductase (activiation of methionine synthase); THF, tetrahydrofolate; TCN2, transcobalamin-II (vitamin B12 transport).