Fig. 6.

Average drainage of pleural effusion during the chemotherapy. The change of the amount of drained pleural effusion during the chemotherapy. The patient received three cycles of oral melphalan/prednisolone therapy (thin arrow indicates the start of chemotherapy), and 2 cycles of intravenous bevacizumab at the first day of the fourth, and 3 weeks later (thick arrows). The average amount of pleural drainage decreased significantly following the addition of bevacizumab (p<0.01) and no pleural drainage was detectable 8 weeks after the completion of the second bevacizumab therapy.