Table 1.
Peptide | Sequence | Number of histidine |
Number of lysine |
a Net charge | b Charge ratio | a PI | |
---|---|---|---|---|---|---|---|
pH=7.4 | pH=5.5 | ||||||
LL-1 | FLGALWKALSKLL | 0 | 2 | 2.0 | 2.0 | 1.0 | 10.6 |
LL-1a | FLGALWHALSKLL | 1 | 1 | 1.0 | 1.7 | 1.7 | 10.0 |
LL-1b | FLGALWKALSHLL | 1 | 1 | 1.0 | 1.7 | 1.7 | 10.0 |
LL-1c | FLGALWHALSHLL | 2 | 0 | 0.1 | 1.5 | 15 | 7.6 |
Theoretical calculation [20]
Positive charge ratios of peptides at pH=5.5 verse at pH= 7.4