Table 1.
Comparison of photographic approaches
| 1999-2004a | 2004-2009b | |
|---|---|---|
| Photographic approach | Serial DELM photography | TB photography |
| Time for initial visit (clinical exam and photography) |
30-50 min | 20-30 min |
| Time for follow-up visit (exam and photo comparison) |
30-50 min | 10-20 min |
| Patients with ≥1 follow-up visit | 297 | 467 |
| Monitoring period | 3-52 (median 22) months | 2-54 (median 24) months |
| Biopsies on follow-up visits | 324 (1.1 per patient) | 275 (0.59 per patient), p<.001 |
| Melanomas on follow-up visits | 6 (2 MIS, 4 invasive) 0.020 per patient |
12 (7 MIS, 5 invasive) 0.026 per patient, p=.81 odds ratio 0.81 (0.24-2.28)c |
| Melanoma detection rate on follow-up visits |
1.9% (nevus : melanoma ratio = 53) 2.2%d (nevus : melanoma ratio = 45)d |
4.4%, p=.093 odds ratio 2.41 (0.82-7.95)c (nevus : melanoma ratio = 22) 5.5%, p=.088d odds ratio 2.57 (0.88-8.51)d (nevus : melanoma ratio = 17)d |
| Depth of invasive melanomas on follow-up visits |
0.23-0.35 mm | 0.19-0.65 mm |
| Derivation of melanomas on follow-up visits |
1/6 nevus-derived (1 DN) |
3/12 nevus-derived, p=1.0 odds ratio 1.61 (0.096-100)c (1 CN, 2 DN) |
a
As described in Fuller et al.16
b
Present study.
c
Odds ratios (95% confidence intervals) computed with second odds (present study) in numerator.
d
Excluding lesions biopsied without photographic change.