Chemical hypoxia increases whole cell conductance. A: representative experiment showing effect of 100 μM DNP and 5 mM DG, and subsequent washout, on whole cell currents. B: current (I)-voltage (V) relationship using data from A, showing that DNP and DG increased whole cell conductance (I/V) and hyperpolarized the cell membrane. C: summary of effect of DNP and DG, and subsequent washout, on whole cell conductance (n = 7; *P = 0.005 compared with control, **P = 0.05 compared with DNP and DG).