Fig. 2.

Representative hematoxylin and eosin-stained liver sections from ad libitum chow-fed rats (chow), rats fed high-fat diets via total enteral nutrition (Control); fed control diets supplemented with 1.7 g·kg⁻¹·day⁻¹ N-acetylcysteine (NAC); fed isocaloric diets with EtOH at 12 g·kg⁻¹·day⁻¹ (EtOH), or fed EtOH diet + 1.7 g·kg⁻¹·day⁻¹ NAC (EtOH + NAC) as described in materials and methods. Magnification ×200. NAC rats exhibited predominantly microsteatosis accompanied by appearance of scattered ballooning hepatocytes (arrowhead). EtOH and EtOH + NAC rats exhibited predominantly macrosteatosis (arrows).