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. Author manuscript; available in PMC: 2011 Jul 1.
Published in final edited form as: Muscle Nerve. 2010 Jul;42(1):14–21. doi: 10.1002/mus.21650

Figure 4.

Figure 4

(A) Congo red stain shows amyloid deposited in the smooth muscle layer of a skeletal muscle arteriole in patient 3. (B) Using polarized light, the green birefringence of amyloid is seen. (C) In a consecutive serial section, dysferlin deposition is seen in this same blood vessel (NCL-Hamlet Novocastra Laboratories Ltd.). (D) In the same section a blood vessel wall lacks dysferlin deposition; only the autofluorescence of the internal elastic membrane (tunica intima) and adventitia (tunica externa) can be seen, but the smooth muscle of the tunica media is devoid of dysferlin.