. 2010 Sep 22;39(2):567–577. doi: 10.1093/nar/gkq806

Table 3.

Conservation of the nucleotide determining the optimal or the suboptimal context of dAUG (purine or pyrimidine at position –3 relative to dAUG, correspondingly), in genes with different contexts of sAUG

Nucleotide at position –3 relative to dAUG	Purine		Pyrimidine
Nucleotide at position –3 relative to dAUG	Optimal sAUG (%)	Suboptimal sAUG (%)	Optimal sAUG (%)	Suboptimal sAUG (%)
Vertebrates	97.7	98.6***	97.0	96.6
Insects	95.7	97.4***	95.2	95.5
Yeast	97.0	96.9	96.0	95.1

Asterisks denote significance of difference between optimal and suboptimal sAUG (chi-square test): ***P < 0.001; **P < 0.01; *P < 0.05.

Table shows the percentage of conserved context-determining purines and pyrimidines for dAUGs in codon positions 2–30 (0 corresponds to sAUG; codon 1 was not analyzed as it always carries a purine—the adenine of the sAUG—at position –3).