Table 5.
Gene set enrichment in genes with suboptimal context of sAUG and a dAUG present among codons 2–5 in human
| Category | Term | Count | % | P-value |
|---|---|---|---|---|
| GOTERM_BP_FAT | GO:0051254∼positive regulation of RNA metabolic process | 18 | 9 | 7.65E-04 |
| GOTERM_BP_FAT | GO:0045893∼positive regulation of transcription, DNA-dependent | 18 | 9 | 7.65E-04 |
| GOTERM_BP_FAT | GO:0045941∼positive regulation of transcription | 18 | 9 | 0.002729 |
| GOTERM_BP_FAT | GO:0045944∼positive regulation of transcription from RNA polymerase II promoter | 14 | 7 | 0.002746 |
| UP_SEQ_FEATURE | domain:EF-hand 1 | 7 | 3.5 | 0.003219 |
| UP_SEQ_FEATURE | domain:EF-hand 2 | 7 | 3.5 | 0.003219 |
| GOTERM_BP_FAT | GO:0010628∼positive regulation of gene expression | 18 | 9 | 0.003422 |
| INTERPRO | IPR011992:EF-Hand type | 8 | 4 | 0.00345 |
| GOTERM_CC_FAT | GO:0005886∼plasma membrane | 47 | 23.5 | 0.006591 |
| UP_SEQ_FEATURE | calcium-binding region:2 | 6 | 3 | 0.006667 |
| UP_SEQ_FEATURE | domain:EF-hand 4 | 5 | 2.5 | 0.006821 |
| UP_SEQ_FEATURE | domain:EF-hand 3 | 5 | 2.5 | 0.006821 |
| GOTERM_BP_FAT | GO:0045935∼positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | 18 | 9 | 0.011303 |
| SP_PIR_KEYWORDS | Transcription | 39 | 19.5 | 0.011644 |
| GOTERM_CC_FAT | GO:0044459∼plasma membrane part | 26 | 13 | 0.013469 |
All genes with suboptimal context of sAUG were used as the background set.
Fifteen categories with the lowest P-values are listed.