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. 2010 Sep 3;39(2):414–428. doi: 10.1093/nar/gkq780

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© The Author(s) 2010. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 7. — AbrB/Abh binding to actively transcribed regions. (A) Examples of AbrB/Abh binding to coding regions of highly transcribed genes are shown. The AbrB/Abh binding profiles in four strains are depicted as in Figure 2A. The gene organization of selected regions is indicated in the middle. Below the gene map, transcriptional signals (y-axis) of each probe in the selected regions are presented separately for Watson (+) and Crick (–) strands. (B) A scatter plot of log₂ binding intensity values of AbrB to intergenic regions (x-axis) and log₂ expression ratios of downstream genes in ΔabrB cells compared to those in wild-type cells (y-axis). If AbrB bound to the intergenic region of divergently transcribed genes, we plotted the expression ratios of both genes. (C) Scatter plot of log₂ binding intensity values of AbrB to coding regions (x-axis) and log₂ expression ratios of AbrB-bound genes in ΔabrB cells compared to those in wild-type cells (y-axis). (D) The results shown in (B) and (C) are merged.