Table 1.
Possible binding profiles |
Molecules expected to be bounda |
Assigned PBRs |
Binding motif | |||||||
---|---|---|---|---|---|---|---|---|---|---|
Profile ID | AbrB in wild | AbrB in Δabh | Abh in wild | Abh in ΔabrB | AbrB homomer | AbrB/Abh heteromer | Abh homomer | Number | % | |
P01 | • | • | • | • | • | • | • | 60 | 37.3 | TNCCAWWWWTGGNA |
P02 | • | • | • | – | • | • | – | 46 | 28.6 | WWWWWCCAWWWWTGG |
P03 | • | • | – | – | • | – | – | 29 | 18 | not clear |
P04 | – | – | – | • | – | – | • (ΔabrB) | 13 | 8.1 | TGGNAWTNCCA |
P05 | • | – | • | – | – | • | – | 5 | 3.1 | |
P06 | • | – | • | • | – | • | • | 4 | 2.5 | |
P07 | • | – | – | – | • (wild) | – | – | 3 | 1.9 | |
P08 | • | • | – | • | • | – | • (ΔabrB) | 1 | 0.6 | |
P09 | • | – | – | • | • (wild) | – | • (ΔabrB) | 0 | 0 | |
P10 | – | • | • | • | • (Δabh) | – | • | 0 | 0 | |
P11 | – | • | • | – | • (Δabh) | • (wild) | 0 | 0 | ||
P12 | – | • | – | • | • (Δabh) | – | • (ΔabrB) | 0 | 0 | |
P13 | – | • | – | – | • (Δabh) | – | – | 0 | 0 | |
P14 | – | – | • | • | – | – | • | 0 | 0 | |
P15 | – | – | • | – | – | – | • (wild) | 0 | 0 |
aIf AbrB/Abh binding is expected to occur in a particular genetic background, it is indicated in parentheses.