Figure 4.

Improved cross-presentation efficiency on early dendritic cells and late dendritic cells. Interleukin-2 concentration in supernatant was measured by ELISA when RF33.70 cells were coincubated for 24 hours with dendritic cells harvested at six days A) or dendritic cells harvested at 13 days, B) pulsed with PEI–OVA nanoparticles. Data are presented as mean ± SD, n = 4, **P < 0.01 versus OVA solution group.

Abbreviations: ELISA, enzyme-linked immunosorbent assay; PEI, polyethyleneimine; OVA, ovalbumin.