Table 3.
Correlative relationship between the percentage of WM at risk and cognitive measures
| Region WMHpa | MMSEb | Visual-spatial | Executive function | Trail Making Test B | WAIS-R Digit Symbol |
|---|---|---|---|---|---|
| Total | −0.02 (0.83) | −0.16 (0.06) | −0.22 (0.007) | 0.29 (<0.001) | −0.15 (0.07) |
| Periventricular | −0.02 (0.81) | −0.15 (0.07) | −0.23 (0.005) | 0.30 (<0.001) | −0.16 (0.05) |
| Subcortical | −0.02 (0.80) | −0.16 (0.06) | −0.22 (0.009) | 0.28 (<0.001) | −0.14 (0.09) |
| Frontal | −0.02 (0.80) | −0.14 (0.09) | −0.20 (0.01) | 0.31 (<0.001) | −0.12 (0.14) |
| Temporal | 0.02 (0.78) | −0.15 (0.08) | −0.25 (0.002) | 0.30 (<0.001) | −0.19 (0.03) |
| Parietal | −0.03 (0.73) | −0.16 (0.06) | −0.22 (0.009) | 0.27 (<0.001) | −0.14 (0.08) |
| Occipital | −0.07 (0.41) | −0.06 (0.45) | −0.17 (0.05) | 0.14 (0.10) | −0.17 (0.05) |
Abbreviations: WMHp, percentage of white matter at risk; MMSE, Mini-Mental State Examination; WAIS, Wechsler Adult Intelligence Scale.
a
Percentages were calculated in the four main lobes and radial location.
b
Converted to MMSE from the Short Test of Mental Status to assist in interpretability.
Note: Values shown are Spearman rank-order correlation (P-value)