Table 4.
Adipose Measure (Quintile Cutpoints) | Men |
|||||
Person-Years | No. of Strokes | HRa | 95% CI | HRb | 95% CI | |
Body mass index, kg/m2 | ||||||
Quintile 1 (<23.4) | 3,109 | 39 | 1.00 | Referent | 1.00 | Referent |
Quintile 2 (23.4–25.2) | 3,299 | 36 | 0.93 | 0.59, 1.46 | 0.93 | 0.59, 1.47 |
Quintile 3 (25.3–26.8) | 3,390 | 35 | 0.87 | 0.55, 1.38 | 0.86 | 0.54, 1.37 |
Quintile 4 (26.9–29.1) | 3,406 | 31 | 0.80 | 0.50, 1.28 | 0.78 | 0.48, 1.25 |
Quintile 5 (>29.1) | 3,325 | 40 | 1.11 | 0.71, 1.73 | 1.09 | 0.69, 1.71 |
Ptrend | 0.91 | 0.99 | ||||
Body mass index at age 50 years, kg/m2 | ||||||
Quintile 1 (<23.4) | 3,356 | 34 | 1.00 | Referent | 1.00 | Referent |
Quintile 2 (23.4–24.8) | 3,406 | 37 | 1.08 | 0.68, 1.72 | 1.06 | 0.66, 1.69 |
Quintile 3 (24.9–26.2) | 3,260 | 40 | 1.30 | 0.82, 2.05 | 1.30 | 0.82, 2.06 |
Quintile 4 (26.3–28.2) | 3,411 | 32 | 0.96 | 0.59, 1.56 | 0.97 | 0.60, 1.58 |
Quintile 5 (>28.2) | 3,097 | 38 | 1.29 | 0.81, 2.05 | 1.29 | 0.81, 2.07 |
Ptrend | 0.45 | 0.43 | ||||
Fat mass, kg | ||||||
Quintile 1 (<23.1) | 3,137 | 36 | 1.00 | Referent | 1.00 | Referent |
Quintile 2 (23.1–27.9) | 3,396 | 35 | 0.99 | 0.62, 1.57 | 0.98 | 0.61, 1.57 |
Quintile 3 (28.0–32.0) | 3,469 | 34 | 0.95 | 0.59, 1.51 | 0.94 | 0.58, 1.50 |
Quintile 4 (32.1–37.6) | 3,358 | 33 | 1.02 | 0.63, 1.65 | 0.98 | 0.61, 1.59 |
Quintile 5 (>37.6) | 3,168 | 43 | 1.44 | 0.92, 2.25 | 1.42 | 0.90, 2.23 |
Ptrend | 0.14 | 0.18 | ||||
Fat-free mass, kg | ||||||
Quintile 1 (<32.6) | 2,931 | 37 | 1.00 | Referent | 1.00 | Referent |
Quintile 2 (32.6–36.6) | 3,278 | 35 | 0.92 | 0.58, 1.46 | 0.94 | 0.59, 1.49 |
Quintile 3 (36.7–39.9) | 3,312 | 35 | 0.90 | 0.57, 1.43 | 0.93 | 0.58, 1.48 |
Quintile 4 (40.0–43.5) | 3,523 | 41 | 1.09 | 0.69, 1.71 | 1.09 | 0.69, 1.73 |
Quintile 5 (>43.5) | 3,484 | 33 | 0.87 | 0.54, 1.40 | 0.86 | 0.53, 1.39 |
Ptrend | 0.86 | 0.80 | ||||
Waist circumference, cm | ||||||
Quintile 1 (<89.5) | 3,349 | 42 | 1.00 | Referent | 1.00 | Referent |
Quintile 2 (89.5–94.4) | 3,323 | 33 | 0.84 | 0.53, 1.32 | 0.83 | 0.53, 1.31 |
Quintile 3 (94.5–99.1) | 3,277 | 40 | 1.06 | 0.69, 1.64 | 1.05 | 0.68, 1.62 |
Quintile 4 (99.2–104.9) | 3,410 | 27 | 0.67 | 0.41, 1.09 | 0.66 | 0.40, 1.07 |
Quintile 5 (>104.9) | 3,170 | 39 | 1.09 | 0.70, 1.69 | 1.05 | 0.67, 1.64 |
Ptrend | 0.95 | 0.79 | ||||
Hip circumference, cm | ||||||
Quintile 1 (<95.0) | 3,324 | 48 | 1.00 | Referent | 1.00 | Referent |
Quintile 2 (95.0–98.9) | 3,780 | 33 | 0.62 | 0.40, 0.97 | 0.60 | 0.38, 0.93 |
Quintile 3 (99.0–101.9) | 3,010 | 31 | 0.75 | 0.48, 1.18 | 0.72 | 0.46, 1.14 |
Quintile 4 (102.0–106.4) | 3,325 | 32 | 0.74 | 0.47, 1.16 | 0.72 | 0.46, 1.13 |
Quintile 5 (>106.4) | 3,090 | 37 | 0.89 | 0.58, 1.37 | 0.86 | 0.56, 1.33 |
Ptrend | 0.80 | 0.73 | ||||
Waist/hip ratio | ||||||
Quintile 1 (<0.92) | 3,432 | 34 | 1.00 | Referent | 1.00 | Referent |
Quintile 2 (0.92–0.95) | 3,356 | 47 | 1.47 | 0.95, 2.29 | 1.46 | 0.94, 2.27 |
Quintile 3 (0.96–0.97) | 3,297 | 29 | 0.89 | 0.54, 1.46 | 0.89 | 0.54, 1.46 |
Quintile 4 (0.98–1.00) | 3,281 | 39 | 1.27 | 0.80, 2.01 | 1.25 | 0.79, 1.98 |
Quintile 5 (>1.00) | 3,163 | 32 | 1.08 | 0.67, 1.76 | 1.02 | 0.63, 1.67 |
Ptrend | 0.98 | 0.82 | ||||
Waist/height ratio | ||||||
Quintile 1 (<0.51) | 3,310 | 41 | 1.00 | Referent | 1.00 | Referent |
Quintile 2 (0.51–0.54) | 3,454 | 35 | 0.81 | 0.51, 1.27 | 0.80 | 0.51, 1.26 |
Quintile 3 (0.55–0.57) | 3,336 | 39 | 0.93 | 0.60, 1.43 | 0.90 | 0.58, 1.41 |
Quintile 4 (0.58–0.61) | 3,215 | 28 | 0.70 | 0.44, 1.14 | 0.69 | 0.42, 1.11 |
Quintile 5 (>0.61) | 3,214 | 38 | 0.97 | 0.63, 1.51 | 0.94 | 0.60, 1.47 |
Ptrend | 0.73 | 0.60 |
Abbreviations: CI, confidence interval; HR, hazard ratio.
Adjusted for age and race (black, nonblack).
Adjusted for age, race (black, nonblack), smoking status (never, former, current), physical activity, alcoholic drinks/week (0, <7, 7–13, ≥14), educational attainment (less than high school, high school graduate, college or higher), and serum creatinine.